During the past 25 years genetic methods for the suppression or eradication of insect pests have become a reality. Genetic pest suppression is unique among biological control methods in that it involves the release of genetically modified insects to control the same Species; thus, these methods are autocidal. The best known, and a well accepted, autocidal control method is the sterile insect technique (sit). Compared with chemical control methods, genetic methods are unparalleled in specificity and safety because only one species in the ecosystem is affected and virtually no chemicals are used. Although genetic methods are applicable to any sexually reproducing insect species, most major sit programs have involved Dipteran species. To many entomologists, sit and screwworms are almost synonymous.

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